Could you please elaborate a bit more on the exact functionality you need to achieve.
Where are the mentioned buttons placed. If they are placed in the content page with the DataList control you could wrap the buttons into asp Panel and add a setting in the RadAjaxManagerProxy on the content page in which this panel updates the dataList.
If the buttons are placed on the MasterPage, you could use the FindControl() method to find the dataList in the Masterpage pageLoad event and add programmatic settings to the main RadAjaxManager there as described here
Here are some other useful resources you could use in setting your application:
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