The Dynamic Language Runtime (more info here) is a great way to spice up those boring old CLR applications. Not only has the DLR helped bring the dynamic keyword to C# 4, but it helps Python and Ruby live on top of .NET.
Using the DLR and IronPython, it's relatively easy to craft a calculated column, giving you the power to execute IronPython expressions over your data objects. What's more, you can import Python modules such as math, datetime, etc.
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