I have a radbutton that works with a validation group to check a drop down before showing a confirmation popup. I have found the OnClientClicked is firing before the validation is complete. I'm wondering if this could be related to the current issue with the radbutton and the Q1 2013 release. I am currently running last night's internal build.
<telerik:RadScriptBlock runat="server"> <script type="text/javascript"> function VALIDATEME(sender, args) { args.set_cancel(!window.confirm('Validate?')); } </script></telerik:RadScriptBlock><telerik:RadButton ID="SaveButton" runat="server" CausesValidation="true" CommandName="Save" Text="Save" OnClientClicked="VALIDATEME" ValidationGroup="Save" /><telerik:RadComboBox ID="combo" runat="server" /><asp:RequiredFieldValidator ID="validator" runat="server" ControlToValidate="combo" ValidationGroup="Save" InitialValue="" ErrorMessage="Error!" Text="*" /><asp:ValidationSummary ID="ValidationSummary" runat="server" ValidationGroup="Save" />