Hello John,
The Content page Page_Load event handler is the right place to add AjaxSettings to the RadAjaxManager, but you don`t need to call the AjaxSettings.Clear() method as this will remove every ajax settings in the manager.
For more information on ajaxifying controls in Master/Content page scenarios, please refer to the following help articles:
Hope this helps.
Best Regards,
Konstantin Dikov
Telerik
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