I got the RadControls_for_ASP[1].NET_AJAX_2010_1_309_dev.msi
so I have the controls to aspnet 2.0, 3.5 and 4.0... but dont know what will hapen with de 4.5
The RadControls for ASP.NET AJAX work on the .Net v3.5, 4.0 and 4.5 frameworks. Please have a look at this Telerik product support to check the current .NET framework version support.