You can deploy the controls in the Global Assembly Cache with the help of Gacutil.exe which is installed along with the Visual Studio.
To install the Telerik.Web.UI assembly, open Visual Studio Command Prompt from Start > Programs > Microsoft Visual Studio <VS version>
> Visual Studio Tools and run the gacutil.exe tool with -i parameter. i represent install. Please check the command below.
gacutil.exe -i "C:\Program Files (x86)\Telerik\RadControls for ASP.NET AJAX Q2 2010\Bin40\Telerik.Web.UI.dll"
If you have a shared component that is used in more than one application
then it is always preferable to put those assemblies in the GAC.
Your files will be secure since administrators often protect the system root directory using an Access
Control List (ACL) to control write and execute access. Because the
global assembly cache is installed in the system root directory, it
inherits that directory's ACL. It is recommended that only users with
Administrator privileges be allowed to delete files from the global
Loading assemblies from GAC mean less overhead and security that your
application will always load correct version of .NET library.
Another advantage is multiple copies of assemblies with the same name but different version
information can be maintained in the global assembly cache. The common language runtime checks the global assembly cache for an
assembly that matches the assembly request before probing or using the
codebase information in a configuration file.