RadNumericTextBox by default does not allow introducing non-digit values (non-numeric).
<telerik:RadNumericTextBox ID="RadNumericTextBox1" runat="server"></telerik:RadNumericTextBox>
When typing non-numeric values, the textbox shows a warning like the following figure:
However, both positive and negative values are considered numeric which is allowed.
<telerik:RadNumericTextBox ID="RadNumericTextBox1" runat="server" MinValue="0"></telerik:RadNumericTextBox>
Here is a Demo
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