Hello Antony,
To achieve the desired functionality you could try using the RadAjaxLoadingPanel panel and show it over the controls. I am sending you a simple example which demonstrates that. Additionally more information about RadAjaxLoadingPanel you could find here:
http://www.telerik.com/help/aspnet-ajax/ajax-loadingpanel.html
I hope this helps.
Greetings,
Radoslav
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