You can set a default selected item for the ComboBox in code-behind.
Here is an example how to do that:
sender, System.EventArgs e)
var comboBoxItems = RadComboBox1.Items;
RadTreeView treeView = (comboBoxItems.FindControl(
RadTreeNode treeNode = treeView.FindNodeByText(
RadComboBox1.Text = treeNode.Text;
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