Hello Himanshu,
I have examined your scenario and I may confirm that it is expected to lose the focus after a postback.
What I could suggest for your requirement is that you handle the OnRequestStart and OnResponseEnd client-side events of your RadAjaxManager/RadAjaxPanel to first save the current focused control and then to focus it again after the request.
The following simple example should cover all scenarios correctly:
Hope that helps.
Regards,
Konstantin Dikov
Telerik
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