RadUpload error for 50MB file uploads

[SWETHA MANDAVA]

WEB.CONFIG
<httpRuntime maxRequestLength="2024000" executionTimeout="10000"/>

ASPX
<telerik:RadUpload runat="server" ID="RadUpload1" Skin="WebBlue" ControlObjectsVisibility="None" MaxFileInputsCount="1" ReadOnlyFileInputs="true"></telerik:RadUpload>

When I try uploading locally I could upload 50MB file. But when I tried from server upload stops in middle with an error

404 - File or directory not found.

The resource you are looking for might have been removed, had its name changed, or is temporarily unavailable.

Can anyone reply me on how to handle upload for large files.

Thanks,
Swetha