Could you please let me know what the "ConsigneeTxt" control added in the RadAjaxManager setting is? I would suggest you to try wrap the target textbox as well as the related extender controls into regular asp panel and add this Panel to update itself in the RadAjaxManager settings.
All the best,
the Telerik team
If you want to get updates on new releases, tips and tricks and sneak peeks at our product labs directly from the developers working on the RadControls for ASP.NET AJAX, subscribe to their blog feed