I think disabling Ajax is what might be causing the text field and browse button to disappear. I haven't uploaded directly into a database, but I believe that you should still be able to save it to the DB without disabling Ajax.
As for your RadUrid item, I believe this forum post
by a Telerik team member should explain the details of this. Basically it is essential for RadUpload to function properly, and disabling this string in the URL might be a bit tricky.