Thank you for writing.
You can try pining the column. You can take a look at our product documentation on Pinning and Unpinning Columns. You can also set the AllowColumnReorder when the user hovers the column header to either true or false depending on the columns the user hovers.
I hope this will be useful for you. If you have further questions, do not hesitate to contact us again.
All the best,
the Telerik team
Q2’11 SP1 of RadControls for WinForms is available for download (see what's new); also available is the Q3'11 Roadmap for Telerik Windows Forms controls.