Hi Dave Plummer,
RadUpload provides two properties to access the uploaded files on the server - UploadedFiles and InvalidFiles. Both properties are of type Telerik.Web.UI.UploadedFileCellection and each file in the collection is an instance of the UploadedFile class. The FileName property of that class returns the fully qualified name of the file on the client (IE6 and some older browsers only). To get a file name that is the same for all browsers, use the GetName() method instead.
I suggest you to review the following link for more information about the provided properties and methods of the UploadedFile class - Manipulating Uploaded Files.
The TargetPhysicalFolder property specifies the name of an existing physical path where files should be saved. It is not related to the properties of the UploadedFile class. Please review this link - Saving Files to a Folder.
the Telerik team