Hi bradley baker,
Here is what you need to do: do not set the TargetFolder (nor the TargetPhysicalFolder) properties of the upload. Then, in the event handler of the submit button insert the record in your database and get the ID. Then create the folder with that name and use the SaveAs method of the UploadedFile object to save the file to that folder.
You can check this
help topic for more information.
Regards,
Veselin Vasilev
the Telerik team