Hi Meenakshi,
Why not use the RadAjaxLoadingPanel control, its purpose is this exactly - to show loading indication and to prevent user interaction with the controls during AJAX requests:
http://demos.telerik.com/aspnet-ajax/ajax/examples/loadingpanel/loadingimages/defaultcs.aspx
You can see how to show it over the whole screen here:
http://www.telerik.com/community/code-library/aspnet-ajax/ajax/how-to-make-a-radajaxloadingpanel-span-over-the-whole-page.aspx
Kind regards,
Tsvetina
the Telerik team
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