You can use the RadAjaxManager control to initiate your own AJAX requests on the client. It gives you the possibility to add AJAX functionality to controls that are not specially designed to make AJAX requests.

In this example you can see an integration between a flash object and the RadAjaxManager control. On clicking upon fixed regions an AJAX request is made with an argument whose value is the name of the area. The result is a short description of the selected continent or country:

// this method is invoked from the flash animation
function InitiateAsyncRequest(arguments)
{
    var ajaxManager = <%= RadAjaxManager1.ClientID %>;
    ajaxManager.AjaxRequest(arguments);
}