Binding multiple selected to RadComboBox after getting the data not work
xaml code <telerik:RadComboBox ItemsSource="{Binding Skills}"
                                     SelectedItem="{Binding SelectedSkillItems,Mode=TwoWay}"
                                     Placeholder="Select Skills"
                                     MaximumWidthRequest="{OnPlatform WinUI='300', MacCatalyst='300'}"
                                     SelectionMode="Multiple"
                                     IsDropDownClosedOnSelection="False"/> 
 public ObservableCollection<string> Skills { get; set; }
 public ObservableCollection<string> SelectedSkillItems 
        {
            get => selectedSkillItems;
            set =>UpdateValue(ref selectedSkillItems, value);
        }
Skills = new ObservableCollection<string>()
            {
                ".NET MAUI",
                "Xamarin",
                "Blazor",
                "WPF",
                "WinUI",
                "Fiddler",
                "Sitefinity",
                "Test Studio",
                "Open Edge",
                "Kinvey",
                "DataRPM",
                "Corticon"
            };
        
 SelectedSkillItems =new ObservableCollection<string>(new List<string>() { "Xamarin", "WPF" });
 

For multiple selection mode use the ComboBox.SelectedItems collection. Example is provided here: https://github.com/telerik/maui-samples/blob/5e0097e9c3410a14fb254d13e2d1c66ad33ceebf/Samples/SdkBrowser/Examples/ComboBoxControl/FeaturesCategory/SelectionExample/Selection.xaml#L39
The SelectedSkillItems property form the ViewModel must be bound to the Combobox.SelectedItems property, not to the SelectedItem.