I seem to be having some issues with a TreeListView placed inside a Grid with a single Row with Height="*" (as indicated here http://docs.telerik.com/devtools/wpf/controls/radgridview/troubleshooting/performance), with some severe performance issues when scrolling either vertically or horizontally: TreeListCellsPanel.MeasureOverride seems to be a bottleneck, and placing a breakpoint at this method indicates that this function is called successively with availableSize equals to either {0; 26} or {+Inf, +Inf}. Adding more rows or columns makes this even worse.