Thank you for contacting Telerik support.
There is no way to create such binding where the database will be automatically updated depending on the items in the autocompletebox. In this case you can use the AutoCompleteDataSource
properties to set the auto complete items (they will be available in the drop down). Then you can subscribe to the CollectionChanged event of the Items
collection and make the appropriate changes to the database there.
I hope this information helps. Should you have any other questions, I will be glad to assist you.
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