For detailed information on .NET Frameworks Support refer to the Product Support Lifecycle
IMPORTANT: It is a prerequisite to have ASP.NET AJAX installed when using Telerik UI for ASP.NET AJAX. Furthermore, note that since Q1 2010 Telerik UI for ASP.NET AJAX .NET 3.5 binaries require .NET 3.5 SP1.
See Browser Support for more information.
Seamless interoperability with jQuery.