Note that most of the forum threads are reviewed by Telerik representatives and sometimes we address the questions asked by our customers in the forums as well. However, a post in the forum doesn't guarantee you a response from the Telerik support team. Moreover, threads are handled according to license and time of posting, so we suggest you use a support ticket, which would be handled before a forum thread.
Storing the changes in a BindingSource back to the database is a geenral programming question. You can refer to the following threads which are quite useful on this topic:
I hope this information helps.