If you place a CheckBox in the CellTemplate of a GridViewColumn, you will be able to manipulate the CheckBox directly, without entering edit mode in RadGridView. Without entering edit mode, the CellEditEnded event will not fire. I propose to set the IsReadOnly property of the CheckBox in the CellTemplate to true, so that clicking it will enter edit mode and display the CheckBox in the CellEditTemplate. This way, when the CheckBox is manipulated, the CellEditEnded event will fire.
the Telerik team
Browse the videos here>>
to help you get started with RadControls for Silverlight