Hi Trevor,
Could you please share a bit more information with us. Fore example: which mouse events you are looking for, does your application use the RadControls?
You will not be able to receive notifications for the mouse wheel and right button events. Their handling relies on trapping the respective Html events and in an OOB mode the silverlight plugin is not hosted in an html page and the Html bridge is not available.
Sincerely yours,
Ivan
the Telerik team