After reading a couple posts on here I was able to figure out how to eliminate the need for multiple clicks to check/uncheck a GridViewCheckBox using "EditTriggers" and "AutoSelectOnEdit". Now my problem is when I check or uncheck a checkbox in a RadGridView it doesn't fire the SelectedItem event for the RadGridView. Can anyone tell me how to accomplish this? I need the SelectedItem to be fired so I know which Row has been selected in the RadGridView.