Yes, the WPF RadMap can use images which are generated by Microsoft Deep Zoom composer. But using the same limitations which were noticed in the Silverlight RadMap post (http://www.telerik.com/community/forums/silverlight/map/radmap-as-zoom-pan-custom-image-navigation.aspx
) on original image which is used in the DZC.
1. It must be square.
2. Width and height of the image must be a power of 2 (512x512, 10204x1024, 2048x2048).
3. Width and height of the image must be equal or greater than 512.
Also I should note that our WPF implementation of the standard Silverlight MultiScaleImage does not support all features of original control. It supports the functionality which is necessary for the RadMap control only.
I have attached the WPF sample solution which uses the same image as the Silverlight project. I hope it helps.
the Telerik team