Hi Karanjit Siyan,
The RadUploadHandler is the default server endpoint for the upload and you can extend it by inheriting it.
Using the RadUpload with RiaServices is possible. For example if you store images, you can keep just the image path in your business object (and DB). Retrieving the image can happen as an absolute url from your server or via a handler.
What you need is to updated your DB after the upload has completed.
This KB article can get you started on processing files on upload:
All the best,
the Telerik team
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