Hi David Kurcharski,
There are few ways to do it. For example:
1. When customer turns on/off a layer you remove all items from the information layer (use RemoveAll method on items collection) and then add items from the selected shape files.
2. The RadMap control supports the usage of multiple information layers. So you can load every shape file to a separate information layer and then turn on/of the corresponding layers when user selects a shape file.
the Telerik team
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