We only have an example that uses ADO.NET to insert the uploaded files into a database. You can find it here.
However, indeed it is a good idea to prepared integration example using OpenAccess. I will post a follow up here when we have the example ready and running
All the best,
the Telerik team
If you want to get updates on new releases, tips and tricks and sneak peeks at our product labs directly from the developers working on the RadControls for ASP.NET AJAX, subscribe to their blog feed