Is it possible for you to upgrade to the latest version of RadEditor, which now is 5.5.0.
In order to get it you should go to the Downloads section under your account, click on the Visual Studio Extensions, DLLs, Scripts, Source Code, DNN and MOSS wrappers ... link and download the RadEditor for MOSS: (zip, 13 MB) installation. You can see the attached screenshot for more information.
1. Make sure that you correctly extend your site with ASP.NET AJAX. You can find instructions in the following help articles.
1. Extending your MOSS site with Microsoft ASP.NET AJAX 1.0
2. Extending your MOSS site with Microsoft ASP.NET AJAX 3.5
2. Follow the upgrade instructions Upgrade Instructions from version 4.x to version 5.x.
Also I attache the help for the 4.5.4 version of RadEditor for MOSS. There you can review the following article. How-to ->
Different configuration files for different webs.
I hope this helps.
the Telerik team