Speaking in general, such behavior can be reproduced when the cells of RadGridView are accessed directly and their value is modified. Such approach is highly not recommended, as it interferes with the virtualization mechanism that the control provides. When the user scrolls, the cell containers are being reused, thus unpredictable results can be experienced. Such operations need to be performed on data level through data binding instead. More information can be found in the UI Virtualization
topic. Are you using such an approach on your end, or I am missing something?
In addition, you may find the Getting Started
topic of RadGridView's online help useful.
Hope this helps.
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