The SqlGeospatialDataReader supports reading the geometry data using WKB (well known binary) or WKT (well known text) formats. For example the following online sample uses IEnumerable data source with geometry in WKT format without using any SQL servers:
So, I think it will not be a problem with using SQLite if it's able to provide geometry data in WKB or WKT formats.
the Telerik team
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