I already answered your other thread and for your convenience and for others who might have the same question I pasted my reply below:
There is no way to achieve what you want without using an additional update panel and this is not directly related to RadControls but to the way AJAX works. Let me explain in brief what is actually happenning in your case. The link button is inside the RadToolTip and since this is a LOD AJAX tooltip, this means that all teh tooltip content is in an update panel and this button is a trigger for updating this update panel. This means that when you click the button, you update only this part of the page which is inside the tooltip. In order to update another part of the page you should wrap it also in an update panel because this is how update panels work - if an update panel is updated, only this part of the page gets updated. This being said, the only possible solution is to also update the other part ofg the page you need by using another update panel.
I hope that my explanation is detailed enough and clear, let me know if you have additional questions.
the Telerik team