I am not quite sure if I understand your question correctly, but if you want to rebind RadGrid, I believe that this help article
will be of help. Another option is (if you are using RadAjax) to use ajaxRequest() for that purpose - this approach is used in the Editing RadGrid demo
(check the refreshGrid() function in the parent page and RadAjaxManager1_AjaxRequest() in codebehind.
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