You can find how to use jQuery with Telerik RadControls for ASP.NET AJAX in the following online help article: http://www.telerik.com/help/aspnet-ajax/using-jquery.html
Reading the functionality, which you want to implement, in order to advise you further I will need some additional information. Please describe what you are trying to achieve with a sample scenario. A couple of screen shots will be helpful as well.
the Telerik team
Registration for Q1 2011 What’s New Webinar Week is now open. Mark your calendar for the week starting March 21st and book your seat
for a walk through all the exciting stuff we ship with the new release!