Yes, this can be achieved quite easy. Here are the steps:
1) Declare RadAsyncUpload without setting TargetFolder. Like this:
2) In the FileUploaded event add the uploaded files to a generic List<UploadedFile>
sender, EventArgs e)
sender, FileUploadedEventArgs e)
3) In the Click handler for the Submit button use the files collection to save them as attachments.
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