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We were using RadAjaxManagerProxy on master page and RadAjaxManager on content page.
Based on the feedback in the following article we have change RadAjaxManagerProxy on content page and RadAjaxManager on master page.http://www.telerikwatch.com/2008/05/optimization-tips-using.html
In our case now we have master page which consists, A Header ToolBar control + RadAjaxManager, Content page consists RadTabStrip + RadAjaxManagerProxy and controls consists RadAjaxManagerProxy.
On any Ajax request we are getting following exception
Microsoft JScript runtime error: 'childNodes' is null or not an object..
on following line of JS
Sys.UI.Control=function(a){Sys.UI.Control.initializeBase(this);this._element=a;a.control=this};
it was working when when we have RadAjaxManagerProxy on master page. Please suggest.