We have clients who are using RadControls for ASP.NET AJAX with Cisco VPN. If there is a problem, it is due the configuration of the VPN. In the post of my colleague you can find the following line "they suggested a workaround - enabling the Smart Tunnel option for the site's bookmark".
I suggest you to contact the Cisco VPN administrator and check if this option is enabled.
All the best,
the Telerik team
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