Since you are already using an expression for the PictureBox you might as well check if its value is valid using IIf
in the expression and perhaps even provide a default value for the image in such a case.
However the issue with your image seems to be the fact that your user does not have access to the image as the inner exception informs. In that case you will have to figure out which image is causing this and either move it or provide permissions.
the Telerik team
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