Ok I am having some very odd behavior.
For one when running a site wiht telerik controls in firefox I don't get the skin, and none of my buttons that cause a rad window to pop up work. They work finr in IE.
The other issue is in IE everything works great untill you hit the refresh button. If you hit the refresh button you get the same behavior as Firefox, rad windows won't work, don't get skins. But if you expand or collapse a grid group you get th eskins and the rad windows work again. but instead of having the nice clean url
Everything works fine with out using the rewrite.
More info when I hit the error in ie I get 'Sys' is undefined
don't seem to get an error in firefox