In this case you will have to handle the SelectionChanged event of the RadComboBox and commit the changes once a value is selected from it:
this.RadGridView1.AddHandler(RadComboBox.SelectionChangedEvent, new Telerik.Windows.Controls.SelectionChangedEventHandler(comboSelectionChanged), true);
private void comboSelectionChanged(object sender, Telerik.Windows.Controls.SelectionChangedEventArgs e)
if (e.RemovedItems.Count != 0)
//this ensures a selection from the drop down is performed.
the Telerik team
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