spec will work out of the box, but for libraries that have DOM dependencies or any other browser-API dependencies we should make additional work to enable them to work in NativeScript. Of course there will be some JS libraries that will not be supported at all due to their dependencies.
My request to you is to list your favorite JS libraries you want to see working with NativeScript. We will make a research if it will be possible to support them in NativeScript out of the box. Here is the initial list of libraries we selected below to start our research: