This is know issue. It seems related to the way fonts are embedded in PDF files that are created by Crystal Reports.
We are working on new text rendering system that should handle such cases correctly, and it should be ready for the 2013 Q1 release (expected in February or March). We will appreciate if you can send us sample document that we can test against the new rendering system in order to be sure that it works correctly for your case.
the Telerik team