Yes, there should be no problems about this scenario. However, you should be aware that the pager is not aware of hierarchical data and you will only be able to page over the root level of items.
the Telerik team
Do you want to have your say when we set our development plans? Do you want to know when a feature you care about is added or when a bug fixed? Explore the Telerik Public Issue Tracking
system and vote to affect the priority of the items.