Thanks for reply,
I am able to load the cssFile by updateing the ToolsFiles.xml file as per your suggestion.
In my scenario i am getting only one UID for all the subsites. I have also created guids.config file but single GUID in comming for all the subsites, so i am unable to create saprate config files for each subsites.
I have also created the ToolsFile.xml file with actual GUID (SPWeb.ID) of the subsite. But it is not accepting this GUID, only root site guid is working.
So still I am not able to load the style as per current subsite.
Is there no way to set the cssFiles using c# code?
I have used this code but it is not giving the results.
Telerik.Web.UI.EditorCssFile _mycss = new Telerik.Web.UI.EditorCssFile("/EDCAPP/CustomColumns/Style/MyStyle.css");